The latency column roughly corresponds to different min-latency settings (see set-min-latency).
The performance model which generates the estimate essentially models the time synchronization mechanism which keeps the virtual time in different cells in sync. It is important to note that the model does not factor in target behavior changes due to a differing latency setting, and this is often a major factor.
The lowest latency to be modeled can be specified with the enable-mtprof.